The actress helped the TV host say goodbye to The Ellen DeGeneres Show after 19 seasons by appearing on the final episode. It was truly a full-circle moment as Aniston was DeGeneres' first guest when the show debuted back in 2003. Aniston appeared on the program 20 times and knows how emotional these series finales can be. DeGeneres asked how she dealt with the ending of Friends after its 10-year run. "Well, I got a divorce and went into therapy," Aniston quipped. "Oh! And then I did a movie called The Break-Up. I just kind of leaned into the end. I just was like, let's just end everything and start new.' It worked great." Friends ended in 2004, and Aniston and her then-husband Brad Pitt divorced in 2005 after nearly five years of marriage. Both remarried, but these relationships also came to an end. Still, Aniston told ELLE in 2018 she considers her marriages "very successful." As she put it, "When they came to an end, it was a choice that was made because we chose to be happy, and sometimes happiness didn't exist within that arrangement anymore."